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KMID : 0376219860230020341
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Chonnam Medical Journal
1986 Volume.23 No. 2 p.341 ~ p.348
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A Study on the Offending Allergens of Bronchial Asthma
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Abstract
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In order to evaluate the offending allergens of bronchial asthma in the area of Chonnam Provincial district, skin prick tests with 102 kinds of allergen were performed in 272 patients with bronchial asthma who visited Chonnam University Hospital in Kwangju and St. Colomban Hospital in Mokpo from July, 1982 to August, 1985.
The results were as follows;
1. The positivity of prick skin tests to 102 sorts of allergen performed in the. patients with bronchial asthma was 57.4% (156 of 276 cases). While the perennial type showed 52.3% of positive reaction, the seasonal asthmatic type showed higher positivity (84.4%).
2. In one hundred fifty-six patient with positive skin responses, the frequency of positivity was 73.1% for house dust and mite, 50.0% for animal epithelia, 27.6% for pollens, 26.3% for fungi and so on.
3. As the number of positive allergens in each subject, 14.7% of all patients was responded to only one kind of allergen, 55.8% was 2 to 4 kinds, 18% was 5 to 7 kinds. Accordingly most of patients (85.3%) reacted to more than 2 kinds of allergen.
4. Among the individual allergen, house dust produced the highest incidence of positive reaction (44.2%), followed by D. farinae (40.4%), D. pteronyssinus (35.3%) and cat fur-(33.3%) decreasingly.
The major allergens of 102 kinds tested proved to be 18 kinds, to which at least more than 5% of the patients showed a positive reaction. And 146 cases (93.6%) among 156 cases with positive reaction to all of the allergens showed responses to one or more major allergen.
5. In the seasonal asthmatic group showing positive skin reaction, pollens such as grass and tree ones were major allergens in March to May group, and in June to August fungi, house dust and mite were dominant and in September to November pollens such as weeds pollen were more prevalent.
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